Alvin Kamara

Seattle's strong run defense and New Orleans' banged-up offensive line make it tough for Kamara to get big runs or touchdowns this week, so he's risky. Sit him in regular leagues that don't give a full point for every catch, and only start him if your league pays full points for catches or you're using him as a cheap pick in daily fantasy.

He’s the Saints’ main running back and should get most of the early carries and some catches, so I’d start him this week. That said, he got hardly any targets last game and the 49ers play slow, so if you have a back who catches a lot of passes you could sit him, and think about trading him later if someone offers good value.

Start Alvin Kamara — he should get most of the catches out of the backfield and Arizona was dead last at stopping running backs who catch passes. If your league gives points for each catch he’s a clear start, but if Spencer Rattler is the quarterback his rushing chances might be cut, so check the starter and snap reports before kickoff.

Draft him in the middle rounds. He catches a lot of passes so he usually gives steady points, but he's turning 30, has some injury history, and the Saints' offense and quarterback situation could keep him from big weeks — I'm a bit unsure.