Brandon Aiyuk

Pick up Brandon Aiyuk now if you have bench space — he’s ahead of his knee rehab and could be back around Week 5 or 6 and be a big part of the 49ers’ offense. Don’t put him in your lineup until he’s officially cleared and practicing fully, since he may be eased in with limited snaps at first; if your league has very small benches, wait until he’s activated.

He's listed out/limited with a knee issue and didn't practice fully, so don't start him this week. If you have room on your bench or an injured-player spot, keep him there and watch practice reports and the game-day inactive list for any late changes.

He's on the injured list with a serious knee injury and won’t be ready for the first few games, so only add him if you can stash him on your injured-list spot or you have an extra bench spot and patience. Watch the practice reports — the return date could move, and he shouldn’t be in your lineup early.

Only pick him in the late rounds as a bench stash if you can hold an injured player; he just had knee surgery and will probably miss the first month or so. He could help later in the season, but don’t draft him earlier unless you’re getting a big discount.