Kenneth Walker III

Start Kenneth Walker III — Charbonnet looks likely to miss or be limited, so Walker should get most of the carries, he ran really well last week, and the Saints have been soft on running backs; just check the final injury report before kickoff.

He's sharing carries and had a smaller role in Week 1, so I wouldn't start him as one of your main running backs this week against a tough Steelers run defense. Keep him as a backup or low-priority option until he's playing at least half the time and getting more touches and catches.

He's expected to be Seattle's lead back, practiced fully, and draws a 49ers run defense that gave up a lot of rushing touchdowns, so start him for Week 1. He missed some preseason and Zach Charbonnet could steal a few touches, so expect a decent but not huge workload — check his game-day status, but play him if he's on your team.

Draft him in the middle rounds — he could be the team’s main runner and catch passes if he stays healthy. He has past foot and leg issues and might split time with Charbonnet, so I’m a bit unsure and you should pick a backup in the late rounds.