Kyler Murray

The 49ers’ defense is tough, so he’s best left on your bench this week. His running has been down and he hasn’t been throwing much, so only play him if you need a risky, all-or-nothing score or have no better QB.

Start Kyler Murray — he makes big plays with his legs and Carolina looked shaky against quarterbacks, so he’s likely to score points this week. Just watch for lots of sacks or turnovers and be ready to swap him out if the game gets messy.

Start Kyler Murray — the Saints were shaky against both the pass and the run last year, Arizona should be in charge, and Murray’s running gives him plenty of ways to score. One expert notes he might run less as he gets older and there’s a minor illness report, so just double-check he’s good to go before kickoff.

Draft Kyler Murray in the middle rounds. He’s a smart pick if you plan to wait on a quarterback — he runs and can have big weeks, but his passing is hit-or-miss and he has health worries, so expect some ups and downs.