New York Giants

Start the Giants defense — the Saints don’t score much and New York’s pass rush makes sacks and turnovers likely. That said, New Orleans has been running and holding the ball more lately, so this is a risky pick only if you’re okay with some swings.

The Giants' defense is a smart play this week because they're at home in cool, low-wind weather, which helps tackling and kicking. The Chiefs can still put up points, so pick the Giants if you want steady scoring and a chance at a big turnover, but go with a riskier option if you need a huge one-week score.

Don't start the Giants defense — they barely got any pressure last week, so they're unlikely to get sacks or turnovers to score many points. Only pick them if you're in a very large league with no better options, and watch for news about their pass rush or injuries that could change things.

Start the Giants' defense this week if you need a cheap pick — the matchup looks favorable, but they’re still largely untested so there’s some risk. Check injury reports, preseason playing time, and weather before kickoff, and if you’re chasing a big prize and want a safer choice, consider a more proven defense.